Controlled Release of Diphosphonates from Synthetic Polymers to Inhibit Calcification

Gershon Golomb*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Calcification is the most frequent cause of the failure of bioprosthetic heart valves fabricated from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Formulation and evaluation of controlled-release drug delivery system to inhibit bioprosthetic heart valve calcification is reviewed.

Original languageEnglish
Pages (from-to)266-289
Number of pages24
JournalJournal of Biomaterials Applications
Volume2
Issue number2
DOIs
StatePublished - Apr 1987

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