TY - JOUR
T1 - Corrigendum
T2 - The Role Played by Mitochondria in FcϵRI-Dependent Mast Cell Activation (Frontiers in Immunology, (2020), 11, (584210), 10.3389/fimmu.2020.584210)
AU - Chelombitko, Maria A.
AU - Chernyak, Boris V.
AU - Fedorov, Artem V.
AU - Zinovkin, Roman A.
AU - Razin, Ehud
AU - Paruchuru, Lakhsmi Bhargavi
N1 - Publisher Copyright:
Copyright © 2020 Chelombitko, Chernyak, Fedorov, Zinovkin, Razin and Paruchuru
PY - 2020/12/11
Y1 - 2020/12/11
N2 - In the original article, there was an error. The statement that mitochondrial ROS inhibit the activity of NEMO is wrong. Mitochondrial ROS are crucial for the activation of the IKK-NEMO complex. A correction has been made to the section The Role Played by Mitochondria in the Fc?RIDependent Mast Cell Activation, subsection Mitochondrial ROS, paragraph 6. The correct paragraph appears below. Mitochondrial ROS can stimulate NF-kB signaling by activating the kinase (IKK) of the inhibitor of NF-kB (IkB), which promotes its proteasome degradation and induces nuclear translocation of NF-kB (81, 84). Mitochondrial ROS-dependent activation of IKK can be mediated by several mechanisms, including the formation of intermolecular disulfide bonds in NF-kB essential modulator (NEMO), a component of the IKK complex (85). The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
AB - In the original article, there was an error. The statement that mitochondrial ROS inhibit the activity of NEMO is wrong. Mitochondrial ROS are crucial for the activation of the IKK-NEMO complex. A correction has been made to the section The Role Played by Mitochondria in the Fc?RIDependent Mast Cell Activation, subsection Mitochondrial ROS, paragraph 6. The correct paragraph appears below. Mitochondrial ROS can stimulate NF-kB signaling by activating the kinase (IKK) of the inhibitor of NF-kB (IkB), which promotes its proteasome degradation and induces nuclear translocation of NF-kB (81, 84). Mitochondrial ROS-dependent activation of IKK can be mediated by several mechanisms, including the formation of intermolecular disulfide bonds in NF-kB essential modulator (NEMO), a component of the IKK complex (85). The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
KW - allergy
KW - FcϵRI-dependent activation
KW - IgE
KW - mast cell
KW - mitochondria
UR - http://www.scopus.com/inward/record.url?scp=85098149700&partnerID=8YFLogxK
U2 - 10.3389/fimmu.2020.620293
DO - 10.3389/fimmu.2020.620293
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C2 - 33362803
AN - SCOPUS:85098149700
SN - 1664-3224
VL - 11
JO - Frontiers in Immunology
JF - Frontiers in Immunology
M1 - 620293
ER -