Cryopreservation of immunological memory and other lymphoid cell functions

David Naor*, Carol O'Toole

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The following components of the immune response by mouse spleen cells were retained after cryopreservation at -110°C: direct and indirect plaque formation, avidity of antibody secreted by plaque forming cells, and induction of primary or secondary adoptive transfer responses. Human peripheral blood lymphocytes retained the capacity to mediate antibody-dependent cytotoxicity and cell mediated immunity to tumor in vitro.

Original languageEnglish
Pages (from-to)361-370
Number of pages10
JournalJournal of Immunological Methods
Volume16
Issue number4
DOIs
StatePublished - Aug 1977
Externally publishedYes

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