TY - JOUR
T1 - Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer's Disease
AU - Li, Qin
AU - Rubin, Limor
AU - Silva, Marta
AU - Li, Shuai
AU - Yang, Chao
AU - Lazarovici, Philip
AU - Zheng, Wenhua
N1 - Publisher Copyright:
© 2022 Qin Li et al.
PY - 2022
Y1 - 2022
N2 - Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer's disease (AD). In recent years, the search for effective components derived from medicinal plants in delaying aging and preventing and treating neurodegenerative diseases has been increasing and the number of related publications shows a rising trend. Here, we present a concise, updated review on the preclinical and clinical research progress in the assessment of the therapeutic potential of different traditional Chinese medicines and derived active ingredients and their effect on the signaling pathways involved in AD neuroprotection. Recognized by their multitargeting ability, these natural compounds hold great potential in developing novel drugs for AD.
AB - Aging is associated with the occurrence of diverse degenerative changes in various tissues and organs and with an increased incidence of neurological disorders, especially neurodegenerative diseases such as Alzheimer's disease (AD). In recent years, the search for effective components derived from medicinal plants in delaying aging and preventing and treating neurodegenerative diseases has been increasing and the number of related publications shows a rising trend. Here, we present a concise, updated review on the preclinical and clinical research progress in the assessment of the therapeutic potential of different traditional Chinese medicines and derived active ingredients and their effect on the signaling pathways involved in AD neuroprotection. Recognized by their multitargeting ability, these natural compounds hold great potential in developing novel drugs for AD.
UR - http://www.scopus.com/inward/record.url?scp=85132920314&partnerID=8YFLogxK
U2 - 10.1155/2022/3777021
DO - 10.1155/2022/3777021
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???
C2 - 35746960
AN - SCOPUS:85132920314
SN - 1942-0900
VL - 2022
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 3777021
ER -