TY - JOUR
T1 - Cytomegalovirus infection in pediatric rheumatic diseases
T2 - A review
AU - Eisenstein, Eli M.
AU - Wolf, Dana G.
PY - 2010/5/20
Y1 - 2010/5/20
N2 - Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.
AB - Human cytomegalovirus (HCMV) is familiar to pediatric rheumatologists mainly as a cause of opportunistic disease in pharmacologically immune suppressed patients. However, HCMV also has a variety of immuno-modulatory effects, through which it may influence the course of rheumatic conditions. In this article we discuss the interplay between HCMV and the immune system, and review the clinical manifestations, diagnosis, and treatment of HCMV infection in children with rheumatic disease.
UR - http://www.scopus.com/inward/record.url?scp=77954016532&partnerID=8YFLogxK
U2 - 10.1186/1546-0096-8-17
DO - 10.1186/1546-0096-8-17
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AN - SCOPUS:77954016532
SN - 1546-0096
VL - 8
JO - Pediatric Rheumatology
JF - Pediatric Rheumatology
M1 - 17
ER -