Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness

Keyphrases

• Tumor Immunotherapy 100%
• Cell Population 100%
• Myeloid-derived Suppressor Cells 100%
• Cytoreductive Surgery 100%
• Antitumor Immune Response 66%
• Advanced Tumor 66%
• AdV-tk 66%
• Lung Cancer 33%
• Flow Cytometry 33%
• Tumor 33%
• Late-onset 33%
• Antitumor 33%
• Therapeutic Potential 33%
• CD8+ T Cells 33%
• Tumor Microenvironment 33%
• Murine Model 33%
• Surgical Resection 33%
• Antitumor Effect 33%
• Type I Interferon 33%
• Immune Defense 33%
• Virus Neutralization 33%
• Early Disease 33%
• Adenoviral Vector 33%
• Advanced Disease 33%
• Advanced Cancer 33%
• Depletion Method 33%
• Rational Therapeutics 33%
• Suicide Gene 33%
• Early-stage Lung Cancer 33%
• Immunosuppressive Network 33%
• Leukocyte Depletion 33%
• Immunotherapeutic Approaches 33%
• Late-stage Cancer 33%
• T Cell Trafficking 33%
• Vector Encoding 33%
• Secondary Cytoreductive Surgery 33%

Medicine and Dentistry

• Neoplasm 100%
• Immunotherapy 100%
• Cell Population 100%
• Myeloid Suppressor Cell 100%
• Disease 42%
• Lung Cancer 28%
• Immune Response 28%
• Immunosuppressive Drug 28%
• Cancer Staging 28%
• Cytoreductive Surgery 28%
• Cell Migration 14%
• Tumor Microenvironment 14%
• Leukopenia 14%
• Surgery 14%
• Flow Cytometry 14%
• Cytotoxic T-Cell 14%
• Adenovirus Vector 14%
• Myeloid-Derived Suppressor Cell 14%
• Immunity 14%
• Interferon Type I 14%
• Neutralization 14%

Immunology and Microbiology

• Immunotherapy 100%
• Cell Population 100%
• Myeloid Suppressor Cell 100%
• Immunosuppressive Drug 40%
• Immune Response 40%
• Cancer Staging 40%
• Cell Migration 20%
• Neutralization 20%
• Murine 20%
• interferon 20%
• Cytotoxic T-Cell 20%
• Myeloid-Derived Suppressor Cell 20%
• Leukocyte 20%
• Immunity 20%
• Adenovirus Vector 20%