D-glucose-induced second harmonic generation response in human erythrocytes

Dmitry Lev*, Alexander Puzenko, Alexandra Manevitch, Zacharia Manevitch, Leonid Livshits, Yuri Feldman, Aaron Lewis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The first experimental results of the nonresonant second harmonic generation (SHG) studies of human erythrocytes membrane exposed to various glucose concentrations in phosphate buffered saline (PBS solution) are presented in this article. It is shown that the SHG signal from the membrane can be altered as a function of glucose concentration. The link between the variation of the SHG intensity and the membrane dielectric permittivity with glucose is established both theoretically and experimentally by comparison with time domain dielectric spectroscopy (TDDS) measurement data.

Original languageAmerican English
Pages (from-to)2513-2518
Number of pages6
JournalJournal of Physical Chemistry B
Issue number8
StatePublished - 26 Feb 2009


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