TY - JOUR
T1 - Demonstration of a high-intensity neutron source based on a liquid-lithium target for Accelerator based Boron Neutron Capture Therapy
AU - Halfon, S.
AU - Arenshtam, A.
AU - Kijel, D.
AU - Paul, M.
AU - Weissman, L.
AU - Berkovits, D.
AU - Eliyahu, I.
AU - Feinberg, G.
AU - Kreisel, A.
AU - Mardor, I.
AU - Shimel, G.
AU - Shor, A.
AU - Silverman, I.
AU - Tessler, M.
N1 - Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - A free surface liquid-lithium jet target is operating routinely at Soreq Applied Research Accelerator Facility (SARAF), bombarded with a ~1.91 MeV, ~1.2 mA continuous-wave narrow proton beam. The experiments demonstrate the liquid lithium target (LiLiT) capability to constitute an intense source of epithermal neutrons, for Accelerator based Boron Neutron Capture Therapy (BNCT). The target dissipates extremely high ion beam power densities (>3 kW/cm2, >0.5 MW/cm3) for long periods of time, while maintaining stable conditions and localized residual activity. LiLiT generates ~3×1010 n/s, which is more than one order of magnitude larger than conventional 7Li(p,n)-based near threshold neutron sources. A shield and moderator assembly for BNCT, with LiLiT irradiated with protons at 1.91 MeV, was designed based on Monte Carlo (MCNP) simulations of BNCT-doses produced in a phantom. According to these simulations it was found that a ~15 mA near threshold proton current will apply the therapeutic doses in ~1 h treatment duration. According to our present results, such high current beams can be dissipated in a liquid-lithium target, hence the target design is readily applicable for accelerator-based BNCT.
AB - A free surface liquid-lithium jet target is operating routinely at Soreq Applied Research Accelerator Facility (SARAF), bombarded with a ~1.91 MeV, ~1.2 mA continuous-wave narrow proton beam. The experiments demonstrate the liquid lithium target (LiLiT) capability to constitute an intense source of epithermal neutrons, for Accelerator based Boron Neutron Capture Therapy (BNCT). The target dissipates extremely high ion beam power densities (>3 kW/cm2, >0.5 MW/cm3) for long periods of time, while maintaining stable conditions and localized residual activity. LiLiT generates ~3×1010 n/s, which is more than one order of magnitude larger than conventional 7Li(p,n)-based near threshold neutron sources. A shield and moderator assembly for BNCT, with LiLiT irradiated with protons at 1.91 MeV, was designed based on Monte Carlo (MCNP) simulations of BNCT-doses produced in a phantom. According to these simulations it was found that a ~15 mA near threshold proton current will apply the therapeutic doses in ~1 h treatment duration. According to our present results, such high current beams can be dissipated in a liquid-lithium target, hence the target design is readily applicable for accelerator-based BNCT.
KW - Accelerator target
KW - Accelerator-based BNCT
KW - Liquid-lithium
KW - Monte-Carlo simulations
UR - http://www.scopus.com/inward/record.url?scp=84959498752&partnerID=8YFLogxK
U2 - 10.1016/j.apradiso.2015.07.045
DO - 10.1016/j.apradiso.2015.07.045
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C2 - 26300076
AN - SCOPUS:84959498752
SN - 0969-8043
VL - 106
SP - 57
EP - 62
JO - Applied Radiation and Isotopes
JF - Applied Radiation and Isotopes
ER -