Dental Chatter: Bacterial Cross-Talk in the Biofilm of the Oral Cavity

Doron Steinberg*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Dental biofilms are composed of hundreds of bacterial species. These biofilms are diverse biological structures due to the heterogeneity of the many different types of supports in the oral cavity. The bacteria immobilized in these biofilms are exposed to rapid environmental changes such as pH, temperature, nutrition and anti-plaque agents. One mode in which these bacteria adapt in the dental biofilm is by quorum sensing. This cell-cell communication regulates diverse sets of adhesion modes, physiological changes, virulence properties, allowing the bacteria to persist in the dental biofilm under rapid environmental changes. In this review, we will concentrate mostly on the cariogenic bacterium Streptococcus mutans as one of the pivotal microorganisms in the supra-gingival biofilm that plays a major role in dental caries.

Original languageAmerican English
Pages (from-to)273-281
Number of pages9
JournalIsrael Journal of Chemistry
Issue number5
StatePublished - 1 May 2016

Bibliographical note

Publisher Copyright:
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.


  • bacteria
  • biofilm
  • biological activity
  • cell adhesion
  • gene expression
  • oral cavity
  • quorum sensing


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