Dental drug-delivery devices: Local and sustained-release applications

Doron Steinberg, Michael Friedman*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


Dental diseases are among the most prevalent illnesses in humans. Many pharmaceutical dosage forms are used to prevent and treat these diseases. Toothpastes and mouthwashes are two of the most popular dental medicaments. A local delivery application that prolongs the release of the drug in the mouth offers great advantages in preventing and treating caries and periodontal diseases. Sustained-release devices are a relatively new concept in dentistry. This paper describes several types of sustained-release devices that are available commercially or are in the premarketing stage.

Original languageAmerican English
Pages (from-to)425-459
Number of pages35
JournalCritical Reviews in Therapeutic Drug Carrier Systems
Issue number5
StatePublished - 1999
Externally publishedYes


  • Caries
  • Dental sustained-release delivery systems
  • Periodontal diseases


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