Abstract
Optically active derivatives of L-isoxazolo[2,3-a]pyrimidin-4-ylalanine are prepared by the combination of Birch reduction of the phenyl ring of L-phenylalanine, followed by ozonolysis and condensation with 3-amino-5-oxo-4-phenyl-2,5-dihydroisoxazole. Ring cleavage of the five-membered ring by reduction, oxidation and nucleophiles gives pyrimidylalanine derivatives.
| Original language | English |
|---|---|
| Pages (from-to) | 1069-1071 |
| Number of pages | 3 |
| Journal | Journal of the Chemical Society, Perkin Transactions 1 |
| Issue number | 7 |
| DOIs | |
| State | Published - 7 Apr 1997 |
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