TY - JOUR
T1 - Detection of ehrlichial antigen in plasma of beagle dogs with experimental acute Ehrlichia canis infection
AU - Waner, Trevor
AU - Rosner, Miri
AU - Harrus, Shimon
AU - Naveh, Ami
AU - Zass, Rosa
AU - Keysary, Avi
PY - 1996/6
Y1 - 1996/6
N2 - Six beagles were experimentally infected with Ehrlichia canis. All dogs developed typical clinical signs of ehrlichiosis and sero-converted. Ehrlichial antigenemia in the plasma of the infected dogs was detected using a sandwich enzyme-linked immunosorbent assay (ELISA). Ehrlichial antigen was present starting 15-20 days post-infection, after the development of clinical signs and antibody titre to Ehrlichia canis. The appearance of ehrlichial antigen in the plasma for a relatively short and variable period after the clinical and haematological signs, limits its potential as an early diagnostic prognosticator of canine ehrlichiosis.
AB - Six beagles were experimentally infected with Ehrlichia canis. All dogs developed typical clinical signs of ehrlichiosis and sero-converted. Ehrlichial antigenemia in the plasma of the infected dogs was detected using a sandwich enzyme-linked immunosorbent assay (ELISA). Ehrlichial antigen was present starting 15-20 days post-infection, after the development of clinical signs and antibody titre to Ehrlichia canis. The appearance of ehrlichial antigen in the plasma for a relatively short and variable period after the clinical and haematological signs, limits its potential as an early diagnostic prognosticator of canine ehrlichiosis.
KW - Diagnosis-Rickettsia
KW - Dog
KW - ELISA
KW - Ehrlichia canis
UR - http://www.scopus.com/inward/record.url?scp=0029979090&partnerID=8YFLogxK
U2 - 10.1016/0304-4017(95)00902-7
DO - 10.1016/0304-4017(95)00902-7
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C2 - 8966999
AN - SCOPUS:0029979090
SN - 0304-4017
VL - 63
SP - 331
EP - 335
JO - Veterinary Parasitology
JF - Veterinary Parasitology
IS - 3-4
ER -