Detection of herpes simplex virus in gingival tissue.

R. Amit*, A. Morag, Z. Ravid, N. Hochman, J. Ehrlich, Z. Zakay-Rones

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The presence of herpes simplex virus (HSV) antigens was shown by immunofluorescence staining in 26 of 66 (39.3%) specimens of clinically healthy gingiva, but only one sample contained infectious virus. HSV DNA sequences were clearly identified in intact gingival cells by dot blot hybridization in one specimen, and a weak pattern in a second one. Both specimens harbored viral antigens. These findings of viral genome and protein expression suggest that the virus is present in the latent form in the gingiva.

Original languageEnglish
Pages (from-to)502-506
Number of pages5
JournalJournal of Periodontology
Volume63
Issue number6
DOIs
StatePublished - Jun 1992

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