TY - JOUR
T1 - Detection of Leishmania major and Leishmania infantum in cats during an outbreak of cutaneous leishmaniosis in Southern Israel
AU - Kleinerman, Gabriela
AU - Melloul, Sivan
AU - Chaim, Lavie
AU - Mergy, Shani E.
AU - Kaufman, Roi G.
AU - Dagan, Nufar
AU - Nachum-Biala, Yaarit
AU - Kitaichik, Sarah
AU - Gross, Saar
AU - Astman, Nadav
AU - Baneth, Gad
N1 - Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023/7
Y1 - 2023/7
N2 - Prevalence of Leishmania spp. infection was studied in stray cats in two military bases in Southern Israel during a cutaneous leishmaniosis (CL) human outbreak caused by Leishmania major. Human CL cases increased from 0/100 in 2008 to 1.28/100 in 2022 in camp #1, and from 0.17/100 in 2008 to 6.4/100 in 2022, in camp #2. Eight out of 29 cats sampled were Leishmania-seropositive (28 %) and 7/29 (24 %) were internal transcribed spacer 1 (ITS1) PCR-positive, out of which four (14 %) were positive for L. major and three (10 %) for L. infantum. Five positive-cats had skin lesions including ulcers, alopecia and scabs, and five had eye lesions. This is the first report of L. major infection in cats in Israel and one of the first descriptions in felines worldwide. A larger cohort of cats and vector studies are necessary to determine if felids may act as reservoirs or sentinels of human L. major infection.
AB - Prevalence of Leishmania spp. infection was studied in stray cats in two military bases in Southern Israel during a cutaneous leishmaniosis (CL) human outbreak caused by Leishmania major. Human CL cases increased from 0/100 in 2008 to 1.28/100 in 2022 in camp #1, and from 0.17/100 in 2008 to 6.4/100 in 2022, in camp #2. Eight out of 29 cats sampled were Leishmania-seropositive (28 %) and 7/29 (24 %) were internal transcribed spacer 1 (ITS1) PCR-positive, out of which four (14 %) were positive for L. major and three (10 %) for L. infantum. Five positive-cats had skin lesions including ulcers, alopecia and scabs, and five had eye lesions. This is the first report of L. major infection in cats in Israel and one of the first descriptions in felines worldwide. A larger cohort of cats and vector studies are necessary to determine if felids may act as reservoirs or sentinels of human L. major infection.
KW - Cutaneous leishmaniosis
KW - Leishmania infantum
KW - Leishmania major
KW - Outbreak
KW - Stray cats
UR - http://www.scopus.com/inward/record.url?scp=85162910151&partnerID=8YFLogxK
U2 - 10.1016/j.cimid.2023.102006
DO - 10.1016/j.cimid.2023.102006
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C2 - 37356168
AN - SCOPUS:85162910151
SN - 0147-9571
VL - 98
JO - Comparative Immunology, Microbiology and Infectious Diseases
JF - Comparative Immunology, Microbiology and Infectious Diseases
M1 - 102006
ER -
