Developing human erythroid cells grown in transferrin-free medium utilize iron originating from extracellular ferritin

J. M. Leimberg; A. M. Konijn; E. Fibach

doi:10.1002/ajh.10355

Developing human erythroid cells grown in transferrin-free medium utilize iron originating from extracellular ferritin

J. M. Leimberg, A. M. Konijn, E. Fibach^*

^*Corresponding author for this work

Braun School of Public Health and Community Medicine

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;88:3200-3207; Meyron-Holtz EG, et al. Blood 1999;94:3205-3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin-free cultures.

Original language	English
Pages (from-to)	211-212
Number of pages	2
Journal	American Journal of Hematology
Volume	73
Issue number	3
DOIs	https://doi.org/10.1002/ajh.10355
State	Published - 1 Jul 2003

Keywords

Erythroid precursors
Ferritin
Hemoglobin
Iron
Transferrin

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10.1002/ajh.10355

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abstract = "In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;88:3200-3207; Meyron-Holtz EG, et al. Blood 1999;94:3205-3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin-free cultures.",

keywords = "Erythroid precursors, Ferritin, Hemoglobin, Iron, Transferrin",

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AU - Fibach, E.

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N2 - In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;88:3200-3207; Meyron-Holtz EG, et al. Blood 1999;94:3205-3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin-free cultures.

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KW - Erythroid precursors

KW - Ferritin

KW - Hemoglobin

KW - Iron

KW - Transferrin

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ER -

Developing human erythroid cells grown in transferrin-free medium utilize iron originating from extracellular ferritin

Abstract

Keywords

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