Development and efficacy of a vaccine against Streptococcus iniae infection in farmed rainbow trout

A. Eldar, A. Horovitcz, H. Bercovier*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

116 Scopus citations

Abstract

Formalin killed bacteria were used as a vaccine against Streptococcus iniae infections in farmed rainbow trout. A single intraperitoneal injection of this vaccine in trout resulted in specific antibody production detectable for 6 months. Trout vaccinated at 50 g were protected under laboratory (experimental disease) and field conditions (natural disease) for at least 4 months against S. iniae infection. Passive transfer of S. iniae specific antibodies conferred protection. Under field conditions, mortality of non vaccinated trout exceeded 50%, whereas mortality of vaccinated trout did not reach 5%. In addition, vaccinated trout under field conditions gained 20% weight when compared with non vaccinated fish.

Original languageEnglish
Pages (from-to)175-183
Number of pages9
JournalVeterinary Immunology and Immunopathology
Volume56
Issue number1-2
DOIs
StatePublished - May 1997

Keywords

  • Antibody response
  • Fish streptococcosis
  • Onchorynkus mykiss
  • Protection
  • Rainbow trout
  • Streptococcus iniae
  • Vaccine

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