TY - JOUR
T1 - Developmental trajectories in siblings of children with autism
T2 - Cognition and language from 4 months to 7 years
AU - Gamliel, Ifat
AU - Yirmiya, Nurit
AU - Jaffe, Dena H.
AU - Manor, Orly
AU - Sigman, Marian
PY - 2009/8
Y1 - 2009/8
N2 - We compared the cognitive and language development at 4, 14, 24, 36, 54 months, and 7 years of siblings of children with autism (SIBS-A) to that of siblings of children with typical development (SIBS-TD) using growth curve analyses. At 7 years, 40% of the SIBS-A, compared to 16% of SIBS-TD, were identified with cognitive, language and/or academic difficulties, identified using direct tests and/or parental reports. This sub-group was identified as SIBS-A-broad phenotype (BP). Results indicated that early language scores (14-54 months), but not cognitive scores of SIBS-A-BP and SIBS-A-nonBP were significantly lower compared to the language scores of SIBS-TD, and that the rate of development was also significantly different, thus pinpointing language as a major area of difficulty for SIBS-A during the preschool years.
AB - We compared the cognitive and language development at 4, 14, 24, 36, 54 months, and 7 years of siblings of children with autism (SIBS-A) to that of siblings of children with typical development (SIBS-TD) using growth curve analyses. At 7 years, 40% of the SIBS-A, compared to 16% of SIBS-TD, were identified with cognitive, language and/or academic difficulties, identified using direct tests and/or parental reports. This sub-group was identified as SIBS-A-broad phenotype (BP). Results indicated that early language scores (14-54 months), but not cognitive scores of SIBS-A-BP and SIBS-A-nonBP were significantly lower compared to the language scores of SIBS-TD, and that the rate of development was also significantly different, thus pinpointing language as a major area of difficulty for SIBS-A during the preschool years.
KW - Autism
KW - Broad autism phenotype
KW - Cognition
KW - Language
KW - Siblings
UR - http://www.scopus.com/inward/record.url?scp=70349604934&partnerID=8YFLogxK
U2 - 10.1007/s10803-009-0727-2
DO - 10.1007/s10803-009-0727-2
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C2 - 19326200
AN - SCOPUS:70349604934
SN - 0162-3257
VL - 39
SP - 1131
EP - 1144
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 8
ER -