Diabetes and the heart: Could the diabetic myocardium be protected by preconditioning?

Vladimir Vinokur, Gil Leibowitz, Leonid Grinberg, Ron Eliashar, Eduard Berenshtein, Mordechai Chevion*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Both type 1 and type 2 diabetes (insulin-dependent and non-insulin dependent diabetes, respectively) are associated with increased risk for microvascular and macrovascular complications including retinopathy, neuropathy, nephropathy and atherosclerosis. Type 2 diabetes markedly increases the risk for cardiovascular morbidity and mortality, which has major public health implications. In this review, molecular mechanisms pertaining to diabetes-induced heart pathology are addressed.

Original languageAmerican English
Pages (from-to)246-256
Number of pages11
JournalRedox Report
Volume12
Issue number6
DOIs
StatePublished - Dec 2007
Externally publishedYes

Keywords

  • Diabetes
  • Heart
  • Myocardium

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