Diabetes and the heart: Could the diabetic myocardium be protected by preconditioning?

Vladimir Vinokur; Gil Leibowitz; Leonid Grinberg; Ron Eliashar; Eduard Berenshtein; Mordechai Chevion

doi:10.1179/135100007X239289

Diabetes and the heart: Could the diabetic myocardium be protected by preconditioning?

Vladimir Vinokur
, Gil Leibowitz
, Leonid Grinberg
, Ron Eliashar
, Eduard Berenshtein
, Mordechai Chevion^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Both type 1 and type 2 diabetes (insulin-dependent and non-insulin dependent diabetes, respectively) are associated with increased risk for microvascular and macrovascular complications including retinopathy, neuropathy, nephropathy and atherosclerosis. Type 2 diabetes markedly increases the risk for cardiovascular morbidity and mortality, which has major public health implications. In this review, molecular mechanisms pertaining to diabetes-induced heart pathology are addressed.

Original language	English
Pages (from-to)	246-256
Number of pages	11
Journal	Redox Report
Volume	12
Issue number	6
DOIs	https://doi.org/10.1179/135100007X239289
State	Published - Dec 2007

Keywords

Diabetes
Heart
Myocardium

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1179/135100007X239289

Cite this

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abstract = "Both type 1 and type 2 diabetes (insulin-dependent and non-insulin dependent diabetes, respectively) are associated with increased risk for microvascular and macrovascular complications including retinopathy, neuropathy, nephropathy and atherosclerosis. Type 2 diabetes markedly increases the risk for cardiovascular morbidity and mortality, which has major public health implications. In this review, molecular mechanisms pertaining to diabetes-induced heart pathology are addressed.",

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AU - Berenshtein, Eduard

AU - Chevion, Mordechai

PY - 2007/12

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N2 - Both type 1 and type 2 diabetes (insulin-dependent and non-insulin dependent diabetes, respectively) are associated with increased risk for microvascular and macrovascular complications including retinopathy, neuropathy, nephropathy and atherosclerosis. Type 2 diabetes markedly increases the risk for cardiovascular morbidity and mortality, which has major public health implications. In this review, molecular mechanisms pertaining to diabetes-induced heart pathology are addressed.

AB - Both type 1 and type 2 diabetes (insulin-dependent and non-insulin dependent diabetes, respectively) are associated with increased risk for microvascular and macrovascular complications including retinopathy, neuropathy, nephropathy and atherosclerosis. Type 2 diabetes markedly increases the risk for cardiovascular morbidity and mortality, which has major public health implications. In this review, molecular mechanisms pertaining to diabetes-induced heart pathology are addressed.

KW - Diabetes

KW - Heart

KW - Myocardium

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Diabetes and the heart: Could the diabetic myocardium be protected by preconditioning?

Abstract

Keywords

UN SDGs

Access to Document

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