Dielectric relaxation measurements of 12 kbp plasmid DNA

D. J. Bakewell; I. Ermolina; H. Morgan; J. Milner; Y. Feldman

doi:10.1016/S0167-4781(00)00176-7

Dielectric relaxation measurements of 12 kbp plasmid DNA

D. J. Bakewell, I. Ermolina, H. Morgan^*, J. Milner, Y. Feldman

^*Corresponding author for this work

The Institute of Applied Physics

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The dielectric properties of 12 kbp plasmid DNA have been measured as a function of temperature in the range 5°C to 40°C. Time domain reflectometry was used to obtain dielectric data over the frequency range from 200 kHz to 3 GHz. Values of the frequency dependent polarisability per DNA macromolecule have been determined from the measurements. Possible mechanisms that could account for the dielectric dispersion are also discussed, in particular the counterion fluctuation model of Manning-Mandel-Oosawa. (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	151-158
Number of pages	8
Journal	Biochimica et Biophysica Acta - Gene Structure and Expression
Volume	1493
Issue number	1-2
DOIs	https://doi.org/10.1016/S0167-4781(00)00176-7
State	Published - 7 Sep 2000

Keywords

Counterion fluctuation
DNA polarisability
Dielectric spectroscopy

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10.1016/S0167-4781(00)00176-7

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AU - Milner, J.

AU - Feldman, Y.

PY - 2000/9/7

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KW - Dielectric spectroscopy

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Dielectric relaxation measurements of 12 kbp plasmid DNA

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