TY - JOUR
T1 - Dielectric relaxation, rotational diffusion and the heat denaturation transition in aqueous solutions of RNAse A
AU - Feldman, Yu D.
AU - Fedotov, V. D.
PY - 1988/1/15
Y1 - 1988/1/15
N2 - The heat denaturation transition of pancreatic RNAse A was investigated by time-domain spectroscopy. In the temperature interval 5-90°C the protein molecule may be in three states: native, temperature denaturated and unfolded. The heat denaturation process occurs in two stages: In the first stage the system behaves as a macromolecule, maintaining its globular structure and increasing its volume two times and its dipole moment 1.5 times; in the second stage the transition into a statistical coil state Occurs.
AB - The heat denaturation transition of pancreatic RNAse A was investigated by time-domain spectroscopy. In the temperature interval 5-90°C the protein molecule may be in three states: native, temperature denaturated and unfolded. The heat denaturation process occurs in two stages: In the first stage the system behaves as a macromolecule, maintaining its globular structure and increasing its volume two times and its dipole moment 1.5 times; in the second stage the transition into a statistical coil state Occurs.
UR - http://www.scopus.com/inward/record.url?scp=0000337990&partnerID=8YFLogxK
U2 - 10.1016/0009-2614(88)87386-X
DO - 10.1016/0009-2614(88)87386-X
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AN - SCOPUS:0000337990
SN - 0009-2614
VL - 143
SP - 309
EP - 312
JO - Chemical Physics Letters
JF - Chemical Physics Letters
IS - 3
ER -