Differences between hybridizable RNA during growth and differentiation of Physarum polycephalum

I. Chet*, H. P. Rusch

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The differences between hybridizable RNA during growth and during differentiation (spherulation) of the slime mold Physarum polycephalum were studied. Two modified methods were used for characterization of the classes of hybridizable RNA, according to their mobility on polyacrylamide gels. It was found that some heavier classes of RNA were depressed or quantitatively diluted during spherulation, compared with growth, whereas new classes are synthesized during the process. Most of the new classes have s-values lower than 10 S. These findings confirm the suggestions previously made that some classes of RNA are depressed during spherulation, whereas new classes are synthesized. This is consistent with the idea about the importance of transcription in differentiation.

Original languageEnglish
Pages (from-to)478-483
Number of pages6
JournalBBA Section Nucleic Acids And Protein Synthesis
Volume213
Issue number2
DOIs
StatePublished - 8 Aug 1970
Externally publishedYes

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