Abstract
Diffusional mass transfer across a serial 2 or 3 unit laminate barrier of ethyl cellulose and polyethylene glycol membranes was studied using caffeine and salicylic acid as model drugs. The overall membrane diffusional resistance was found to be the sum of the intrinsic membrane resistances. When the resistance of one layer was much higher than that of the others, the permeability was then controlled by the single layer in the laminate.
Original language | English |
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Pages (from-to) | 1417-1420 |
Number of pages | 4 |
Journal | International Journal of Clinical Pharmacy |
Volume | 2 |
Issue number | 1 |
DOIs | |
State | Published - Dec 1980 |