TY - JOUR
T1 - Direct access to polycyclic imidazolium salts via decarboxylative condensation of α-enaminones with proline
AU - Simha, Yuval
AU - Daniels, Gil
AU - Goldman, Amalya
AU - Kuniavsky, Elihay
AU - Tsvelikhovsky, Dmitry
N1 - Publisher Copyright:
© 2023 The Royal Society of Chemistry.
PY - 2023/5/29
Y1 - 2023/5/29
N2 - A new strategy for direct access to fully substituted polycyclic imidazolium salts, based on the interaction of α-enaminones with proline in the presence of variety of counter-ions, is reported. The developed open-flask operation is catalyst-, metal-, and Lewis acid-free green process, which requires no ion-exchange step, not limited to aryl substituents, and generally results in good yields and minimal formation of side products.
AB - A new strategy for direct access to fully substituted polycyclic imidazolium salts, based on the interaction of α-enaminones with proline in the presence of variety of counter-ions, is reported. The developed open-flask operation is catalyst-, metal-, and Lewis acid-free green process, which requires no ion-exchange step, not limited to aryl substituents, and generally results in good yields and minimal formation of side products.
UR - http://www.scopus.com/inward/record.url?scp=85161641260&partnerID=8YFLogxK
U2 - 10.1039/d3gc00896g
DO - 10.1039/d3gc00896g
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AN - SCOPUS:85161641260
SN - 1463-9262
VL - 25
SP - 5916
EP - 5921
JO - Green Chemistry
JF - Green Chemistry
IS - 15
ER -