Direct access to polycyclic imidazolium salts via decarboxylative condensation of α-enaminones with proline

Yuval Simha, Gil Daniels, Amalya Goldman, Elihay Kuniavsky, Dmitry Tsvelikhovsky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A new strategy for direct access to fully substituted polycyclic imidazolium salts, based on the interaction of α-enaminones with proline in the presence of variety of counter-ions, is reported. The developed open-flask operation is catalyst-, metal-, and Lewis acid-free green process, which requires no ion-exchange step, not limited to aryl substituents, and generally results in good yields and minimal formation of side products.

Original languageAmerican English
Pages (from-to)5916-5921
Number of pages6
JournalGreen Chemistry
Volume25
Issue number15
DOIs
StatePublished - 29 May 2023

Bibliographical note

Publisher Copyright:
© 2023 The Royal Society of Chemistry.

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