Abstract
A new strategy for direct access to fully substituted polycyclic imidazolium salts, based on the interaction of α-enaminones with proline in the presence of variety of counter-ions, is reported. The developed open-flask operation is catalyst-, metal-, and Lewis acid-free green process, which requires no ion-exchange step, not limited to aryl substituents, and generally results in good yields and minimal formation of side products.
Original language | American English |
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Pages (from-to) | 5916-5921 |
Number of pages | 6 |
Journal | Green Chemistry |
Volume | 25 |
Issue number | 15 |
DOIs | |
State | Published - 29 May 2023 |
Bibliographical note
Funding Information:This project was financially supported by Yissum Research Development Company of the Hebrew University of Jerusalem. We thank Dr Aviva Friedman-Ezra for NMR and DSC assistance. We thank Prof. Raed Abu-Reziq for TGA assistance.
Publisher Copyright:
© 2023 The Royal Society of Chemistry.