Distinct Functions of Neutrophil in Cancer and Its Regulation

Zvi Granot*, Jadwiga Jablonska

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

128 Scopus citations

Abstract

Neutrophils are the most abundant of all white blood cells in the human circulation and are usually associated with inflammation and with fighting infections. In recent years the role immune cells play in cancer has been a matter of increasing interest. In this context the function of neutrophils is controversial as neutrophils were shown to possess both tumor promoting and tumor limiting properties. Here we provide an up-to-date review of the pro- and antitumor properties neutrophils possess as well as the environmental cues that regulate these distinct functions.

Original languageAmerican English
Article number701067
JournalMediators of Inflammation
Volume2015
DOIs
StatePublished - 2015

Bibliographical note

Publisher Copyright:
© 2015 Zvi Granot and Jadwiga Jablonska.

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