DNA-membrane association during the mitotic cycle of Physarum polycephalum

Ariella Oppenheim; J. Wahrman

doi:10.1016/0014-4827(73)90447-3

DNA-membrane association during the mitotic cycle of Physarum polycephalum

Ariella Oppenheim^*, J. Wahrman

^*Corresponding author for this work

Faculty of Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Association of DNA with the nuclear membrane was studied in the naturally synchronous slime mold Physarum polycephalum. Sucrose gradient analyses showed that DNA is bound to the membrane during all stages of interphase. The association is labile, but can be stabilized by spermine, which presumably acts on the membrane. Experiments with pulse-labeled DNA suggest that replication does not occur at a membranal site.

Original language	English
Pages (from-to)	287-294
Number of pages	8
Journal	Experimental Cell Research
Volume	79
Issue number	2
DOIs	https://doi.org/10.1016/0014-4827(73)90447-3
State	Published - Jun 1973

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title = "DNA-membrane association during the mitotic cycle of Physarum polycephalum",

abstract = "Association of DNA with the nuclear membrane was studied in the naturally synchronous slime mold Physarum polycephalum. Sucrose gradient analyses showed that DNA is bound to the membrane during all stages of interphase. The association is labile, but can be stabilized by spermine, which presumably acts on the membrane. Experiments with pulse-labeled DNA suggest that replication does not occur at a membranal site.",

author = "Ariella Oppenheim and J. Wahrman",

year = "1973",

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AB - Association of DNA with the nuclear membrane was studied in the naturally synchronous slime mold Physarum polycephalum. Sucrose gradient analyses showed that DNA is bound to the membrane during all stages of interphase. The association is labile, but can be stabilized by spermine, which presumably acts on the membrane. Experiments with pulse-labeled DNA suggest that replication does not occur at a membranal site.

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DNA-membrane association during the mitotic cycle of Physarum polycephalum

Abstract

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