Abstract
An escape from the TRAP: Telomere chains self-assemble into catalytically active hemin-G-quadruplex units. We describe how the resulting DNAzyme units can be used for quantitative analysis of telomerase activity and its inhibitors.
Original language | English |
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Pages (from-to) | 2362-2367 |
Number of pages | 6 |
Journal | ChemBioChem |
Volume | 11 |
Issue number | 17 |
DOIs | |
State | Published - Nov 2010 |
Keywords
- DNAzymes
- G-quadruplexes
- Inhibitors
- Telomerase
- Telomeres