Does iron play a role in Parkinson's disease?

E. R. Bauminger; M. Barcikowska; A. Friedman; J. Galazka-Friedman; D. Hechel; I. Nowik

doi:10.1007/BF02064618

Does iron play a role in Parkinson's disease?

E. R. Bauminger^*, M. Barcikowska, A. Friedman, J. Galazka-Friedman, D. Hechel, I. Nowik

^*Corresponding author for this work

Racah Institute of Physics

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Mössbauer studies of Parkinsonian and control Substantia Nigra (SN) show that the overall amount of iron in SN is about the same in PD and control. At least 90% of this iron is ferritin-like and Fe²⁺ and/or neuromelanin iron, if present at all, can constitute only less than 10% of the overall iron. During storage in formalin, iron is slowly removed from ferritin and bound to a chelating agent.

Original language	English
Pages (from-to)	853-857
Number of pages	5
Journal	Hyperfine Interactions
Volume	91
Issue number	1
DOIs	https://doi.org/10.1007/BF02064618
State	Published - Dec 1994

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10.1007/BF02064618

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@article{40a9471e8a4449de8507c49fea64df8f,

title = "Does iron play a role in Parkinson's disease?",

abstract = "M{\"o}ssbauer studies of Parkinsonian and control Substantia Nigra (SN) show that the overall amount of iron in SN is about the same in PD and control. At least 90\% of this iron is ferritin-like and Fe2+ and/or neuromelanin iron, if present at all, can constitute only less than 10\% of the overall iron. During storage in formalin, iron is slowly removed from ferritin and bound to a chelating agent.",

author = "Bauminger, \{E. R.\} and M. Barcikowska and A. Friedman and J. Galazka-Friedman and D. Hechel and I. Nowik",

year = "1994",

month = dec,

doi = "10.1007/BF02064618",

language = "אנגלית",

volume = "91",

pages = "853--857",

journal = "Hyperfine Interactions",

issn = "0304-3834",