Drug Delivery to Wounds, Burns, and Diabetes-Related Ulcers

The skin’s continuity and integrity can be compromised as a result of trauma arising from physical or thermal damage or an underlying pathological condition resulting in wounds. Wound healing involves three phases: inflammation, proliferation (new tissue formation), and remodeling/contraction. This chapter discussed different wound management dressings and advanced technologies for achieving improved healing for wounds, burns, and diabetes-related ulcers. Several dressings have been used for delivering drugs to acute and chronic wounds. Apart from the dressings, some pharmacological agents that include antibiotic, gene therapy and cytokine, growth factors, and stem cells and other drugs like antioxidants, antihistamines, phenytoin, antisense gel, and traditional drugs have been discussed in the chapter along with the pathogenesis of wounds, burns, and diabetes ulcers.