Dynamic growth program regulated by LANCEOLATE enables flexible leaf patterning

Sharona Shleizer-Burko, Yogev Burko, Ori Ben-Herzel, Naomi Ori*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

During their development, leaves progress through a highly controlled yet flexible developmental program. Transcription factors from the CIN-TCP family affect leaf shape by regulating the timing of leaf maturation. Characterization of mutants in the tomato (Solanum lycopersicum) CIN-TCP gene LANCEOLATE (LA) led us to hypothesize that a threshold LA-like activity promotes leaf differentiation. Here, we examined the relationship between LA activity, leaf maturation, and final leaf size and shape. Leaves of diverse shapes from various Solanaceae species or from different positions on the tomato plant differed in the timing of growth and maturation, and these were often associated with altered LA expression dynamics. Accordingly, genetic manipulations of LA activity in tomato altered leaf growth and maturation, leading to changes in leaf size and shape. LA expression sustained until late stages of tomato leaf development, and stage-specific overexpression of miR319, a negative regulator of CIN-TCP genes, confirmed that LA-like proteins affect leaf development through these late stages. Together, our results imply that dynamic spatial and temporal leaf maturation, coordinated by LA-like genes, enables the formation of variable leaf forms.

Original languageAmerican English
Pages (from-to)695-704
Number of pages10
JournalJournal of Embryology and Experimental Morphology
Volume138
Issue number4
DOIs
StatePublished - 15 Feb 2011

Keywords

  • Leaf development
  • Solanaceae
  • TCP
  • Tomato

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