Early identification and interventions for autism spectrum disorder: Executive summary

Lonnie Zwaigenbaum; Margaret L. Bauman; Roula Choueiri; Deborah Fein; Connie Kasari; Karen Pierce; Wendy L. Stone; Nurit Yirmiya; Annette Estes; Robin L. Hansen; James C. McPartland; Marvin R. Natowicz; Timothy Buie; Alice Carter; Patricia A. Davis; Doreen Granpeesheh; Zoe Mailloux; Craig Newschaffer; Diana Robins; Susanne Smith Roley; Sheldon Wagner; Amy Wetherby

doi:10.1542/peds.2014-3667B

Early identification and interventions for autism spectrum disorder: Executive summary

Lonnie Zwaigenbaum^*, Margaret L. Bauman, Roula Choueiri, Deborah Fein, Connie Kasari, Karen Pierce, Wendy L. Stone, Nurit Yirmiya, Annette Estes, Robin L. Hansen, James C. McPartland, Marvin R. Natowicz, Timothy Buie, Alice Carter, Patricia A. Davis, Doreen Granpeesheh, Zoe Mailloux, Craig Newschaffer, Diana Robins, Susanne Smith RoleySheldon Wagner, Amy Wetherby

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10% to 19%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.

Original language	English
Pages (from-to)	S1-S9
Journal	Pediatrics
Volume	136
DOIs	https://doi.org/10.1542/peds.2014-3667B
State	Published - 1 Oct 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
Copyright © 2015 by the American Academy of Pediatrics.

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Zwaigenbaum, L., Bauman, M. L., Choueiri, R., Fein, D., Kasari, C., Pierce, K., Stone, W. L., Yirmiya, N., Estes, A., Hansen, R. L., McPartland, J. C., Natowicz, M. R., Buie, T., Carter, A., Davis, P. A., Granpeesheh, D., Mailloux, Z., Newschaffer, C., Robins, D., ... Wetherby, A. (2015). Early identification and interventions for autism spectrum disorder: Executive summary. Pediatrics, 136, S1-S9. https://doi.org/10.1542/peds.2014-3667B

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title = "Early identification and interventions for autism spectrum disorder: Executive summary",

abstract = "Autism spectrum disorders (ASDs) are neurodevelopmental disorders characterized by impaired social communication skills and isolated areas of interest.1 The current prevalence of these disorders is estimated to be 1 in 68, 2 and recent estimates of the risk of recurrence in families with at least 1 child diagnosed with ASD are 10% to 19%.3-5 Advances have been made in identifying genetic variants that can account for biological vulnerability to ASD, 6, 7 although recent studies examining patterns of heredity implicate environmental factors and potential gene-by-environment interactions.8 Although the exact etiology remains unknown in most families, some researchers suggest that the pathogenesis of the disorder begins during prenatal life.9, 10 It is likely that ASD is heterogeneous in its etiology as well as in its clinical presentation.",

author = "Lonnie Zwaigenbaum and Bauman, {Margaret L.} and Roula Choueiri and Deborah Fein and Connie Kasari and Karen Pierce and Stone, {Wendy L.} and Nurit Yirmiya and Annette Estes and Hansen, {Robin L.} and McPartland, {James C.} and Natowicz, {Marvin R.} and Timothy Buie and Alice Carter and Davis, {Patricia A.} and Doreen Granpeesheh and Zoe Mailloux and Craig Newschaffer and Diana Robins and Roley, {Susanne Smith} and Sheldon Wagner and Amy Wetherby",

note = "Publisher Copyright: Copyright {\textcopyright} 2015 by the American Academy of Pediatrics.",

year = "2015",

month = oct,

day = "1",

doi = "10.1542/peds.2014-3667B",

language = "אנגלית",

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Zwaigenbaum, L, Bauman, ML, Choueiri, R, Fein, D, Kasari, C, Pierce, K, Stone, WL, Yirmiya, N, Estes, A, Hansen, RL, McPartland, JC, Natowicz, MR, Buie, T, Carter, A, Davis, PA, Granpeesheh, D, Mailloux, Z, Newschaffer, C, Robins, D, Roley, SS, Wagner, S & Wetherby, A 2015, 'Early identification and interventions for autism spectrum disorder: Executive summary', Pediatrics, vol. 136, pp. S1-S9. https://doi.org/10.1542/peds.2014-3667B

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AU - Bauman, Margaret L.

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AU - Kasari, Connie

AU - Pierce, Karen

AU - Stone, Wendy L.

AU - Yirmiya, Nurit

AU - Estes, Annette

AU - Hansen, Robin L.

AU - McPartland, James C.

AU - Natowicz, Marvin R.

AU - Buie, Timothy

AU - Carter, Alice

AU - Davis, Patricia A.

AU - Granpeesheh, Doreen

AU - Mailloux, Zoe

AU - Newschaffer, Craig

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AU - Roley, Susanne Smith

AU - Wagner, Sheldon

AU - Wetherby, Amy

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Early identification and interventions for autism spectrum disorder: Executive summary

Abstract

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