TY - JOUR
T1 - Effect of Different Steroids on Prolactin Secretion in Pituitary-Hypothalamus Organ Co-Culture
AU - Ben-David, M.
AU - Dikstein, S.
AU - Sulman, F. G.
PY - 1964/11
Y1 - 1964/11
N2 - Various steroids were added to pituitary culture or pituitary-hypothalamus co-culture in vitro, and their effect on pro-lactin release was studied. 1. Estradiol and hydrocortisone are strong stimulants of pro-lactin release, apparently acting directly through the pituitary. 2. 3-Alpha-hydroxy-11, 20-diketo-pregnane-3-hemisuccinate and, to a lesser degree, progesterone are depressants of prolactin release, acting directly on the hypophysis. 3. Testosterone does not affect prolactin release from the pituitary.
AB - Various steroids were added to pituitary culture or pituitary-hypothalamus co-culture in vitro, and their effect on pro-lactin release was studied. 1. Estradiol and hydrocortisone are strong stimulants of pro-lactin release, apparently acting directly through the pituitary. 2. 3-Alpha-hydroxy-11, 20-diketo-pregnane-3-hemisuccinate and, to a lesser degree, progesterone are depressants of prolactin release, acting directly on the hypophysis. 3. Testosterone does not affect prolactin release from the pituitary.
UR - http://www.scopus.com/inward/record.url?scp=0345538094&partnerID=8YFLogxK
U2 - 10.3181/00379727-117-29623
DO - 10.3181/00379727-117-29623
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C2 - 14233482
AN - SCOPUS:0345538094
SN - 0037-9727
VL - 117
SP - 511
EP - 513
JO - Experimental Biology and Medicine
JF - Experimental Biology and Medicine
IS - 2
ER -