Effect of erythrocyte aggregation on optical transmission of blood

L. D. Shvartsman*, I. Fine

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

We present here a bird-eye view of time-dependent optical transmission of blood in red-near infrared spectral range. This issue is of the key importance both for fundamental understanding and for various applications connected with non-invasive optical blood analysis. A number of experiments measuring kinetics of blood transmission in the case of natural heart pulsations and of artificial kinetics following over-systolic occlusion is reviewed. The comprehensive theoretical approach has to consider scattering- associated mechanism rather than the widely accepted absorptionassociated one. Light scattering occurs on RBC aggregates. The size of aggregates and their shape change in time due to blood flow variations. It results in the corresponding changes of optical transmission.

Original languageEnglish
Title of host publicationComplex Dynamics and Fluctuations in Biomedical Photonics IV
DOIs
StatePublished - 2007
EventComplex Dynamics and Fluctuations in Biomedical Photonics IV - San Jose, CA, United States
Duration: 20 Jan 200723 Jan 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6436
ISSN (Print)1605-7422

Conference

ConferenceComplex Dynamics and Fluctuations in Biomedical Photonics IV
Country/TerritoryUnited States
CitySan Jose, CA
Period20/01/0723/01/07

Keywords

  • Light scattering
  • Pulse oximetry
  • RBC aggregation
  • Whole blood

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