Effect of linseed oil ingestion on plasma lipid fatty acid composition and platelet aggregability in healthy volunteers

P. Budowski*, Naomi Trostler, M. Lupo, N. Vaisman, A. Eldor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Eight healthy volunteers ingested 60 ml linseed oil over a period of six weeks. Icosapentaenoic acid increased in plasma triglycerides (TG), phospholipids (PL) and cholesteryl esters (CE) but did not exceed mean values of 2%. α-Linolenic acid rose markedly in TG, linoleic acid decreased in TG and CE, and arachidonic acid decreased in PL and CE. Two additional subjects on a similar regimen underwent blood platelet aggregability tests by the collagen threshold procedure. In both cases a striking decrease in platelet sensitivity to collagen was observed. The results show that linseed oil affects the polyunsaturated fatty acid profile of plasma lipids and suggest a possible alteration of platelet aggregability.

Original languageEnglish
Pages (from-to)343-346
Number of pages4
JournalNutrition Research
Volume4
Issue number2
DOIs
StatePublished - 1984

Keywords

  • Linseed oil
  • plasma lipids
  • platelet aggregation

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