Effect of lithium treatment on microsomal ATPase activity in several tissues

Yehuda Gutman*, Sarah Hochman, Dorith Strachman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

1. 1. Treatment with lithium chloride (2 mmol/kg. daily for 14 days) in the rat did not affect Mg++-ATPase or (Na++K+)-dependent ATPase in the brain-stem, cortex, extrapyramidal nuclei, adrenal glands, or mucosa of the small intestine. 2. 2. Microsomal ATPase in the salivary glands increased under lithium: in the parotid (Na++K+)-dependent ATPase increased while in the submaxillary gland the Mg++-ATPase activity was elevated. 3. 3. In the mucosa of the colon Mg++-ATPase was elevated and (Na++K+)-dependent ATPase was reduced after treatment with lithium.

Original languageEnglish
Pages (from-to)315-318
Number of pages4
JournalInternational Journal of Biochemistry
Volume4
Issue number21
DOIs
StatePublished - 1973

Keywords

  • ATPase
  • brain
  • intestinal mucosa
  • Lithium
  • microsomal
  • salivary glands

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