TY - JOUR
T1 - Effects of Daily Adherence to Antihypertensive Medication on Blood Pressure Control
AU - Rose, Adam J.
AU - Glickman, Mark E.
AU - D'Amore, Meredith M.
AU - Orner, Michelle B.
AU - Berlowitz, Dan
AU - Kressin, Nancy R.
PY - 2011/6
Y1 - 2011/6
N2 - Clinicians are often uncertain about how to manage elevated blood pressure (BP) when a patient reports that he/she has recently missed several doses of antihypertensive medications. While we know that better adherence can improve BP during several months, the magnitude of this relationship in the short term is poorly understood. The authors examined this issue using a group of patients who monitored adherence using a Medication Events Monitoring System (MEMS) cap and had BP measurements in the course of routine clinical practice. BP readings were compared following 7days of excellent adherence (100%) or poor adherence (<60%), omitting BP values following intermediate adherence. Using several different methods, BP following 7days of excellent adherence was between 12/7 mm Hg and 15/8mmHg lower than after 7days of poor adherence. Clinicians can use this effect size to calibrate their impressions of what the BP might have been with improved adherence.
AB - Clinicians are often uncertain about how to manage elevated blood pressure (BP) when a patient reports that he/she has recently missed several doses of antihypertensive medications. While we know that better adherence can improve BP during several months, the magnitude of this relationship in the short term is poorly understood. The authors examined this issue using a group of patients who monitored adherence using a Medication Events Monitoring System (MEMS) cap and had BP measurements in the course of routine clinical practice. BP readings were compared following 7days of excellent adherence (100%) or poor adherence (<60%), omitting BP values following intermediate adherence. Using several different methods, BP following 7days of excellent adherence was between 12/7 mm Hg and 15/8mmHg lower than after 7days of poor adherence. Clinicians can use this effect size to calibrate their impressions of what the BP might have been with improved adherence.
UR - http://www.scopus.com/inward/record.url?scp=79958269417&partnerID=8YFLogxK
U2 - 10.1111/j.1751-7176.2011.00427.x
DO - 10.1111/j.1751-7176.2011.00427.x
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C2 - 21649841
AN - SCOPUS:79958269417
SN - 1524-6175
VL - 13
SP - 416
EP - 421
JO - Journal of Clinical Hypertension
JF - Journal of Clinical Hypertension
IS - 6
ER -