Effects of low doses of cyclophosphamide and low doses of irradiation on the regulation of induced erythrocyte autoantibodies in mice

P. Hutchings, D. Naor, A. Cooke

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

This paper describes some of the characteristics of a suppressor cell which is capable of regulating a rat RBC-induced autoantibody response against mouse RBCs. This cell, which appears to function as an inducer of suppression on transfer to naive recipients, is sensitive to low doses of cyclophosphamide, and its generation is affected by low doses of irradiation. However, the recipients of these cells are insensitive to cyclophosphamide treatment, suppression still being indicated in such animals.

Original languageEnglish
Pages (from-to)97-104
Number of pages8
JournalImmunology
Volume54
Issue number1
StatePublished - 1985
Externally publishedYes

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