TY - JOUR
T1 - Effects of propofol as an anaesthetic agent in adult lions (Panthera leo)
T2 - A comparison with two established protocols
AU - Epstein, A.
AU - White, R.
AU - Horowtiz, I. H.
AU - Kass, P. H.
AU - Ofri, R.
PY - 2002
Y1 - 2002
N2 - The aims of this study were to evaluate the effects of a ketamine/propofol anaesthetic protocol in lions (Panthera leo), and to compare it to two commonly used anaesthetic protocols. Seventeen adult lions were anaesthetised using three different protocols. Group XK (n = 6) was anaesthetised with intramuscular (i.m.) injections of xylazine and ketamine. Group KD (n = 5) was anaesthetised with an i.m. injection of ketamine, followed by an intravenous (i.v.) injection of ketamine of diazepam. Group KP (n = 6) was anaesthetised with an i.m. injection of ketamine followed by an i.v. injection of propofol. There was a significant difference in heart rate (P < 0.0002), which was lowest in group XK and highest in KD. Jaw tone was significantly lower in Group XK (P < 0.05). No undesirable effects were noted following injection of the propofol. Propofol was a suitable and safe drug for maintenance of anaesthesia in adult lions.
AB - The aims of this study were to evaluate the effects of a ketamine/propofol anaesthetic protocol in lions (Panthera leo), and to compare it to two commonly used anaesthetic protocols. Seventeen adult lions were anaesthetised using three different protocols. Group XK (n = 6) was anaesthetised with intramuscular (i.m.) injections of xylazine and ketamine. Group KD (n = 5) was anaesthetised with an i.m. injection of ketamine, followed by an intravenous (i.v.) injection of ketamine of diazepam. Group KP (n = 6) was anaesthetised with an i.m. injection of ketamine followed by an i.v. injection of propofol. There was a significant difference in heart rate (P < 0.0002), which was lowest in group XK and highest in KD. Jaw tone was significantly lower in Group XK (P < 0.05). No undesirable effects were noted following injection of the propofol. Propofol was a suitable and safe drug for maintenance of anaesthesia in adult lions.
UR - http://www.scopus.com/inward/record.url?scp=0036084059&partnerID=8YFLogxK
U2 - 10.1053/rvsc.2001.0535
DO - 10.1053/rvsc.2001.0535
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C2 - 12027594
AN - SCOPUS:0036084059
SN - 0034-5288
VL - 72
SP - 137
EP - 140
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 2
M1 - 90535
ER -