Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination

Amihai Rottenstreich; Gila Zarbiv; Esther Oiknine-Djian; Roy Zigron; Dana G. Wolf; Shay Porat

doi:10.1093/cid/ciab266

Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination

Amihai Rottenstreich
, Gila Zarbiv
, Esther Oiknine-Djian
, Roy Zigron
, Dana G. Wolf^*
, Shay Porat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women and infants were positive for anti S- and anti-receptor binding domain antibody-specific immunoglobulin G. Cord blood antibody concentrations were correlated to maternal levels and to time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide maternal and neonatal protection.

Original language	English
Pages (from-to)	1909-1912
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	73
Issue number	10
DOIs	https://doi.org/10.1093/cid/ciab266
State	Published - 16 Nov 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved.

Keywords

Cord blood
Pregnancy
SARS-CoV-2
Serology
Vaccination

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/cid/ciab266

Cite this

Rottenstreich, A., Zarbiv, G., Oiknine-Djian, E., Zigron, R., Wolf, D. G., & Porat, S. (2021). Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination. Clinical Infectious Diseases, 73(10), 1909-1912. https://doi.org/10.1093/cid/ciab266

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abstract = "Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women and infants were positive for anti S- and anti-receptor binding domain antibody-specific immunoglobulin G. Cord blood antibody concentrations were correlated to maternal levels and to time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide maternal and neonatal protection.",

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author = "Amihai Rottenstreich and Gila Zarbiv and Esther Oiknine-Djian and Roy Zigron and Wolf, \{Dana G.\} and Shay Porat",

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month = nov,

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doi = "10.1093/cid/ciab266",

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Rottenstreich, A, Zarbiv, G, Oiknine-Djian, E, Zigron, R, Wolf, DG & Porat, S 2021, 'Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination', Clinical Infectious Diseases, vol. 73, no. 10, pp. 1909-1912. https://doi.org/10.1093/cid/ciab266

Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination. / Rottenstreich, Amihai; Zarbiv, Gila; Oiknine-Djian, Esther et al.
In: Clinical Infectious Diseases, Vol. 73, No. 10, 16.11.2021, p. 1909-1912.

Research output: Contribution to journal › Article › peer-review

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AU - Rottenstreich, Amihai

AU - Zarbiv, Gila

AU - Oiknine-Djian, Esther

AU - Zigron, Roy

AU - Wolf, Dana G.

AU - Porat, Shay

PY - 2021/11/16

Y1 - 2021/11/16

N2 - Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women and infants were positive for anti S- and anti-receptor binding domain antibody-specific immunoglobulin G. Cord blood antibody concentrations were correlated to maternal levels and to time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide maternal and neonatal protection.

AB - Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women and infants were positive for anti S- and anti-receptor binding domain antibody-specific immunoglobulin G. Cord blood antibody concentrations were correlated to maternal levels and to time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide maternal and neonatal protection.

KW - Cord blood

KW - Pregnancy

KW - SARS-CoV-2

KW - Serology

KW - Vaccination

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DO - 10.1093/cid/ciab266

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Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies after Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination

Abstract

Bibliographical note

Keywords

UN SDGs

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