Electrical contacting of glucose oxidase by DNA-templated polyaniline wires on surfaces

Lixin Shi, Yi Xiao, Itamar Willner

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

Poly(aniline-aniline boronic acid) wires are generated on ds-DNA templates, and the resulting wires exhibit redox functions at neutral pH aqueous solutions. The association of flavin adenine dinucleotide (FAD) to the boronic acid ligand followed by the reconstitution of apo-glucose oxidase on the cofactor units yield an integrated enzyme-electrode where the biocatalyst reveals direct electrical contact with the electrode.

Original languageEnglish
Pages (from-to)1057-1060
Number of pages4
JournalElectrochemistry Communications
Volume6
Issue number10
DOIs
StatePublished - Oct 2004

Keywords

  • Apo-glucose oxidase
  • Biosensor
  • DNA template
  • Poly(aniline-aniline boronic acid) wires
  • Reconstitution

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