Electrochemical detection of dopamine by a calixarene-cellulose acetate mixed Langmuir-Blodgett monolayer

Yujuan Xu, Qingli Hao*, Daniel Mandler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The sensing performance of a Langmuir-Blodgett monolayer was significantly improved by controlling the film organization at the air-water interface. Cellulose acetate (CA) and 4-tert-butylcalix [6]arene (calix) were co-spread and formed a Langmuir film, which was efficiently transferred onto a preoxidized gold electrode, Auox. The modified gold electrode was applied as a fast, highly sensitive electrochemical sensing platform for the quantitative determination of a model molecule, dopamine (DA). The modified gold electrode, CA-calix/Auox, demonstrated better recognition and sensing ability towards dopamine as compared with electrodes modified by a single component. Under the optimized conditions, the reduction peak currents at the CA-calix/Auox increased linearly within the concentration range of dopamine from 5 to 100 and 100–7500 nM, and exhibited a very low limit of detection (LOD) of 2.54 nM (S/N = 3). These results suggest a simple, superior and efficient approach for the controllable rearrangement of Langmuir-Blodgett monolayers on a molecular level. The electroanalytical performance was optimized from the perspective of the electrode-electrolyte interface.

Original languageAmerican English
Pages (from-to)29-36
Number of pages8
JournalAnalytica Chimica Acta
Volume1042
DOIs
StatePublished - 26 Dec 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier B.V.

Keywords

  • Calixarene
  • Cellulose acetate
  • Dopamine
  • Electroanalytical chemistry
  • LB film

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