Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

Florina Teodorescu; Laure Rolland; Viswanatha Ramarao; Amar Abderrahmani; Daniel Mandler; Rabah Boukherroub; Sabine Szunerits

doi:10.1039/c5cc05539c

Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

Florina Teodorescu
, Laure Rolland
, Viswanatha Ramarao
, Amar Abderrahmani
, Daniel Mandler
, Rabah Boukherroub
, Sabine Szunerits^*

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiological medium while preserving its biological activity.

Original language	English
Pages (from-to)	14167-14170
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	75
DOIs	https://doi.org/10.1039/c5cc05539c
State	Published - 30 Jul 2015

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry.

Access to Document

10.1039/c5cc05539c

Cite this

@article{10ce0720b1c44e58a45eb050cbaddc29,

title = "Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode",

abstract = "An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4\% of human insulin was released into a physiological medium while preserving its biological activity.",

author = "Florina Teodorescu and Laure Rolland and Viswanatha Ramarao and Amar Abderrahmani and Daniel Mandler and Rabah Boukherroub and Sabine Szunerits",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2015",

month = jul,

day = "30",

doi = "10.1039/c5cc05539c",

language = "אנגלית",

volume = "51",

pages = "14167--14170",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "75",

}

TY - JOUR

T1 - Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

AU - Teodorescu, Florina

AU - Rolland, Laure

AU - Ramarao, Viswanatha

AU - Abderrahmani, Amar

AU - Mandler, Daniel

AU - Boukherroub, Rabah

AU - Szunerits, Sabine

PY - 2015/7/30

Y1 - 2015/7/30

N2 - An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiological medium while preserving its biological activity.

AB - An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiological medium while preserving its biological activity.

UR - https://www.scopus.com/pages/publications/84940986245

U2 - 10.1039/c5cc05539c

DO - 10.1039/c5cc05539c

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 26257079

AN - SCOPUS:84940986245

SN - 1359-7345

VL - 51

SP - 14167

EP - 14170

JO - Chemical Communications

JF - Chemical Communications

IS - 75

ER -

Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this