Electronic Level Structure of Novel Guanine Octuplex DNA Single Molecules

Natalie Fardian-Melamed, Liat Katrivas, Dvir Rotem, Alexander Kotlyar*, Danny Porath*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Throughout the past few decades, guanine quadruplex DNA structures have attracted much interest both from a fundamental material science perspective and from a technologically oriented perspective. Novel guanine octuplex DNA, formed from coiled quadruplex DNA, was recently discovered as a stable and rigid DNA-based nanostructure. A detailed electronic structure study of this new nanomaterial, performed by scanning tunneling spectroscopy on a subsingle-molecule level at cryogenic temperature, is presented herein. The electronic levels and lower energy gap of guanine octuplex DNA compared to quadruplex DNA dictate higher transverse conductivity through guanine octads than through guanine tetrads.

Original languageAmerican English
Pages (from-to)8987-8992
Number of pages6
JournalNano Letters
Issue number21
StatePublished - 10 Nov 2021

Bibliographical note

Publisher Copyright:
© 2021 American Chemical Society.


  • DNA nanoelectronics
  • STM
  • guanine octuplex
  • guanine quadruplex
  • scanning tunneling spectroscopy


Dive into the research topics of 'Electronic Level Structure of Novel Guanine Octuplex DNA Single Molecules'. Together they form a unique fingerprint.

Cite this