TY - JOUR
T1 - Elementary arithmetic operations by enzymes
T2 - A model for metabolic pathway based computing
AU - Baron, Ronan
AU - Lioubashevski, Oleg
AU - Katz, Eugenii
AU - Niazov, Tamara
AU - Willner, Itamar
PY - 2006/2/27
Y1 - 2006/2/27
N2 - (Figure Presented) Physio-logical: A system of four enzymes, horseradish peroxidase, glucose dehydrogenase, glucose oxidase, and catalase, operate in parallel in the presence of NADH and NAD+ to yield AND and XOR gates (see picture). Glucose and H2O2 act as the inputs, and the absorbance that follows the production of gluconic acid or NADH provide the outputs of the AND and XOR gates, respectively.
AB - (Figure Presented) Physio-logical: A system of four enzymes, horseradish peroxidase, glucose dehydrogenase, glucose oxidase, and catalase, operate in parallel in the presence of NADH and NAD+ to yield AND and XOR gates (see picture). Glucose and H2O2 act as the inputs, and the absorbance that follows the production of gluconic acid or NADH provide the outputs of the AND and XOR gates, respectively.
KW - Enzymes
KW - Logic gates
KW - Metabolism
KW - Redox chemistry
UR - http://www.scopus.com/inward/record.url?scp=33746276942&partnerID=8YFLogxK
U2 - 10.1002/anie.200503314
DO - 10.1002/anie.200503314
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C2 - 16440379
AN - SCOPUS:33746276942
SN - 1433-7851
VL - 45
SP - 1572
EP - 1576
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 10
ER -