TY - JOUR
T1 - Enantiomer resolution of nefopam hydrochloride, a novel analgesic
T2 - a study by liquid chromatography and circular dichroism spectroscopy
AU - Isaksson, Roland
AU - Sandström, Jan
AU - Eliaz, Michal
AU - Israely, Zehorith
AU - Agranat, Israel
PY - 1988/1
Y1 - 1988/1
N2 - Abstract— Nefopam, a potent analgesic, has been completely resolved into enantiomers on a preparative scale by low‐pressure liquid chromatography on swollen, microcrystalline triacetylcellulose. The enantiomerically pure hydrochlorides were prepared from the base, and the circular dichroism spectra of the free base and the hydrochloride are reported. 1988 Royal Pharmaceutical Society of Great Britain
AB - Abstract— Nefopam, a potent analgesic, has been completely resolved into enantiomers on a preparative scale by low‐pressure liquid chromatography on swollen, microcrystalline triacetylcellulose. The enantiomerically pure hydrochlorides were prepared from the base, and the circular dichroism spectra of the free base and the hydrochloride are reported. 1988 Royal Pharmaceutical Society of Great Britain
UR - http://www.scopus.com/inward/record.url?scp=0023839165&partnerID=8YFLogxK
U2 - 10.1111/j.2042-7158.1988.tb05148.x
DO - 10.1111/j.2042-7158.1988.tb05148.x
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 2896773
AN - SCOPUS:0023839165
SN - 0022-3573
VL - 40
SP - 48
EP - 50
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
IS - 1
ER -