Abstract
Addition of the cholera toxin B subunit to oral and intranasal proteosome- Shigella flexneri 2a lipopolysaccharide vaccines improved their immunogenicities. Enhancement of anti-O-Shigella immunoglobulin A levels was most evident in lung lavages following oral immunization and in lung and intestinal fluids when suboptimal doses were used with either immunization route.
Original language | English |
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Pages (from-to) | 5198-5200 |
Number of pages | 3 |
Journal | Infection and Immunity |
Volume | 62 |
Issue number | 11 |
State | Published - 1994 |
Externally published | Yes |