TY - JOUR
T1 - Eosinophils
T2 - 'New' roles for 'old' cells
AU - Munitz, A.
AU - Levi-Schaffer, F.
PY - 2004/3
Y1 - 2004/3
N2 - Prominent blood and tissue eosinophilia is manifested in a number of inflammatory states, particularly in allergic diseases. Eosinophils are a source of numerous cytokines and growth factors, thus in principle they can display both pro-inflammatory and anti-inflammatory activities as well as immunoregulatory ones. In this review, we will discuss the cross-talk between eosinophils and other cell types that they come in contact with in the inflammatory milieu, such as mast cells, fibroblasts and endothelial cells. 'New' roles for eosinophils in cancer and novel activatory signals will also be described.
AB - Prominent blood and tissue eosinophilia is manifested in a number of inflammatory states, particularly in allergic diseases. Eosinophils are a source of numerous cytokines and growth factors, thus in principle they can display both pro-inflammatory and anti-inflammatory activities as well as immunoregulatory ones. In this review, we will discuss the cross-talk between eosinophils and other cell types that they come in contact with in the inflammatory milieu, such as mast cells, fibroblasts and endothelial cells. 'New' roles for eosinophils in cancer and novel activatory signals will also be described.
KW - Allergy
KW - Angiogenesis
KW - Eosinophils
KW - Fibrosis
KW - Inhibitory receptors
UR - http://www.scopus.com/inward/record.url?scp=1542405217&partnerID=8YFLogxK
U2 - 10.1111/j.1398-9995.2003.00442.x
DO - 10.1111/j.1398-9995.2003.00442.x
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C2 - 14982507
AN - SCOPUS:1542405217
SN - 0105-4538
VL - 59
SP - 268
EP - 275
JO - Allergy: European Journal of Allergy and Clinical Immunology
JF - Allergy: European Journal of Allergy and Clinical Immunology
IS - 3
ER -
