Eosinophils: 'New' roles for 'old' cells

A. Munitz, F. Levi-Schaffer*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

166 Scopus citations


Prominent blood and tissue eosinophilia is manifested in a number of inflammatory states, particularly in allergic diseases. Eosinophils are a source of numerous cytokines and growth factors, thus in principle they can display both pro-inflammatory and anti-inflammatory activities as well as immunoregulatory ones. In this review, we will discuss the cross-talk between eosinophils and other cell types that they come in contact with in the inflammatory milieu, such as mast cells, fibroblasts and endothelial cells. 'New' roles for eosinophils in cancer and novel activatory signals will also be described.

Original languageAmerican English
Pages (from-to)268-275
Number of pages8
JournalAllergy: European Journal of Allergy and Clinical Immunology
Issue number3
StatePublished - Mar 2004


  • Allergy
  • Angiogenesis
  • Eosinophils
  • Fibrosis
  • Inhibitory receptors


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