Abstract
Several weeks after damage of the sciatic nerve in adult rats, a stable electrical (ephaptic) interaction forms between pairs of injured sensory and motor axons. Fiber-fiber interaction occurs when the nerve ends in a neuroma, after end-to-end nerve suture and after nerve crush injury. Unlike the transient “artificial synapse” created acutely on section of a nerve, this form of crosstalk is long-lasting. Its existence lends support to the hypothesis that ephaptic interaction is an important factor in neurologic pathophysiology.
| Original language | English |
|---|---|
| Pages (from-to) | 1061-1064 |
| Number of pages | 4 |
| Journal | Neurology |
| Volume | 29 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1979 |
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