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Erratum: Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS (Cancer Cell (2017) 31(6) (771–789.e6), (S1535610817302027), (10.1016/j.ccell.2017.05.006))

  • Detian Yuan
  • , Shan Huang
  • , Emanuel Berger
  • , Lei Liu
  • , Nina Gross
  • , Florian Heinzmann
  • , Marc Ringelhan
  • , Tracy O. Connor
  • , Mira Stadler
  • , Michael Meister
  • , Julia Weber
  • , Rupert Öllinger
  • , Nicole Simonavicius
  • , Florian Reisinger
  • , Daniel Hartmann
  • , Rüdiger Meyer
  • , Maria Reich
  • , Marco Seehawer
  • , Valentina Leone
  • , Bastian Höchst
  • Dirk Wohlleber, Simone Jörs, Marco Prinz, Duncan Spalding, Ulrike Protzer, Tom Luedde, Luigi Terracciano, Matthias Matter, Thomas Longerich, Percy Knolle, Thomas Ried, Verena Keitel, Fabian Geisler, Kristian Unger, Einat Cinnamon, Eli Pikarsky, Norbert Hüser, Roger J. Davis, Darjus F. Tschaharganeh, Roland Rad, Achim Weber, Lars Zender, Dirk Haller*, Mathias Heikenwalder*
*Corresponding author for this work

Research output: Contribution to journalComment/debate

Abstract

(Cancer Cell 31, 771–789; June 12, 2017) We, the authors of this publication, investigated how Kupffer cell-derived tumor necrosis factor (TNF), in the context of mitochondrial dysfunction and oxidative stress, promotes cholangiocellular proliferation and intrahepatic cholangiocarcinoma development. We were made aware of a duplication in Figure 6, where the RelA immunofluorescence image in Figure 6B from the Hepatocytic diff group was duplicated as the c-Jun staining in Figure 6E in the TNF + SP600125 group. We also identified that a histology image from the CK19 IHC panel from the Ctrl group in Figure 4H was incorrectly reused in the CK19 IHC panel from the Mock group in Figure S6I. These errors were introduced during the preparation of the figures, and we now provide the revised Figures 6 and S6 below. These corrections do not alter the interpretation and conclusions of the study, and we sincerely apologize for any confusion they may have caused.[Figure

Original languageEnglish
Pages (from-to)444-447
Number of pages4
JournalCancer Cell
Volume44
Issue number2
DOIs
StatePublished - 9 Feb 2026

Bibliographical note

Publisher Copyright:
© 2026 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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