Evaluation framework for carotid bifurcation lumen segmentation and stenosis grading

K. Hameeteman*, M. A. Zuluaga, M. Freiman, L. Joskowicz, O. Cuisenaire, L. Flórez Valencia, M. A. Gülsün, K. Krissian, J. Mille, W. C.K. Wong, M. Orkisz, H. Tek, M. Hernández Hoyos, F. Benmansour, A. C.S. Chung, S. Rozie, M. van Gils, L. van den Borne, J. Sosna, P. BermanN. Cohen, P. C. Douek, I. Sánchez, M. Aissat, M. Schaap, C. T. Metz, G. P. Krestin, A. van der Lugt, W. J. Niessen, T. Van Walsum

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

69 Scopus citations


This paper describes an evaluation framework that allows a standardized and objective quantitative comparison of carotid artery lumen segmentation and stenosis grading algorithms. We describe the data repository comprising 56 multi-center, multi-vendor CTA datasets, their acquisition, the creation of the reference standard and the evaluation measures. This framework has been introduced at the MICCAI 2009 workshop 3D Segmentation in the Clinic: A Grand Challenge III, and we compare the results of eight teams that participated. These results show that automated segmentation of the vessel lumen is possible with a precision that is comparable to manual annotation. The framework is open for new submissions through the website http://cls2009.bigr.nl.

Original languageAmerican English
Pages (from-to)477-488
Number of pages12
JournalMedical Image Analysis
Issue number4
StatePublished - Aug 2011

Bibliographical note

Funding Information:
Reinhard Hameeteman, Wiro Niessen and Theo van Walsum are supported by the Stichting voor de Technische Wetenschappen (STW) of The Netherlands Organization for Scientific Research (NWO). Aad van der Lugt is supported by Netherlands Organization for Health Research and Development (NWO-KF Grant 907-00-122 ) and The Dutch Heart Foundation (Grant 2007B161 ).


  • CTA
  • Carotid
  • Evaluation framework
  • Lumen segmentation
  • Stenosis grading


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